Latex Piezoelectric Immunoassay: Analysis of C-Reactive Protein in Human Serum

Shigeru Kurosawa, Hidenobu Aizawa, and Minoru Yoshimoto

ABSTRACT We constructed an integrated immunosensor system to combine a quartz crystal microbalance with the agglutination reaction of immunized latex beads. C-reactive protein (CRP) induced an immunoreaction due to the latex beads with anti-CRP antibody. We succeeded in determining the concentration of CRP necessary in human serum for disease diagnosis using a CRP Sensor I.

© 2000, by The Institute of Electrical and Electronics Engineers, Inc. All rights reserved.

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